Acute fatigue in endurance athletes: The association between countermovement jump variables and creatine kinase response.


  • Cristian Yánez UDCA



endurance sport, neuromuscular fatigue, monitoring athletes, countermovement jump, CMJ


The purpose of this study was to determine the variables of acute neuromuscular fatigue (NMF) and its correlation with the serum concentration of creatine kinase (CK) pre- and post-training through performance analysis counter movement jump (CMJ). Methods: Eight male endurance performance athletes performed 3 trials CMJ in force platform before and after fatigue protocol high intensity intermittent running (PFAI) (fatiguing to the maximum possible rate of work for each repetition Protocol). A total of 8 variables were analyzed through CMJ and the biomarker CK before and after fatigue protocol. Results: No significant differences for the variables of mean force MF (P = 0,62. d = 0,03), time to peak force TTPF (P = 0,46. d = 0,43), jump height JH (P = 0,19. d = 0,65), flight time FT (P = 0,26. d = 0,58), relation flight time: contraction time FT: CT (P = 0,74. d = 0,59) and CK (P = 0,79. d = 0,31). Significant differences in variables of peak power (p = 0.008. d = 1,37) and contraction time (p = 0.01. d = 0,76) were found. Finally, Spearman’s correlation (Spearman’s Rho) for non-parametric tests was performed between peak power (PP) (p = 0.002) (r = 0.92) and contraction time (CT) (p = 0.001) (r = 0.97). Conclusions: There is a neuromuscular fatigue state in the acute phase determined of CMJ variables, independent of lineal relation CK production. Likewise, it is highlighted a major parameter the reduction of peak power and increment of contraction time in the neuromuscular performance.


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Allen D, Lamb GD, Westerblad H. (2008). Skeletal Muscle Fatigue: cellular mechanisms. Physiological Reviews Published. 88, 287–332. doi: 10.1152/physrev.00015.2007

Bigland Ritchie B, Rice CL, Garland SJ, Walsh ML. (1995). Task dependent factors in fatigue of human voluntary contractions. Adv Exp Med Biol. 384:361-80. doi: 10.1007/978-1-4899-1016-5_29.

Boullosa D, Tuimil J, Alegre L, Iglesias E, Lusquiños F. (2011). Concurrent Fatigue and Potentiation in Endurance Athletes. International Journal of Sports Physiology and Performance. 6, 82-93. doi: 10.1123/ijspp.6.1.82.

Boullosa, D.A., & Tuimil, J.L. (2009). Postactivation potentiation in distance runners after two different field running protocols. Journal of Strength and Conditioning Research, vol 23, 1560-1565. doi: 10.1519/JSC.0b013e3181a3ce61.

Brancaccio, P., Limongelli, F. M., & Maffulli, N. (2006). Monitoring of serum enzymes in sport. British journal of sports medicine, 40(2), 96–97. doi: 10.1136/bjsm.2005.020719.

Brancaccio, P., Maffulli, N., & Limongelli, F. M. (2007). Creatine kinase monitoring in sport medicine. British medical bulletin, 81(1), 209-230. doi: 10.1093/bmb/ldm014.

Brown, LE. (2008). Strength training. NSCA National Strength and Conditioning Association. Pan American Medical Publisher.

Cáceres, R. Á. (1994). Multivariate and non-parametric statistics with SPSS: application to health sciences. Díaz de Santos Editions

Cormack S, Mooney M, Morgan W, McGuigan MR. (2013). Influence of Neuromuscular Fatigue on Accelerometer Load in Elite Australian Football Players. International Journal of Sports Physiology and Performance. 8, 373-378. doi: 10.1123/ijspp.8.4.373.

Cormack SJ, Newton RU, McGuigan MR. (2008). Neuromuscular and endocrine responses of elite players to an Australian Rules Football match. Int J Sports Physiol Perform. 3(3):359–374. doi: 10.1123/ijspp.3.3.359.

Cormack SJ, Newton RU, McGuigan MR, Doyle TL. (2008b) Reliability of measures obtained during single and repeated countermovement jumps. Int J Sports Physiol Perform. 3(2):131–144. doi: 10.1123/ijspp.3.2.131

Cormie, P., McGuigan, M. R., & Newton, R. U. (2010). Adaptations in athletic performance after ballistic power versus strength training. Medicine & Science in Sports & Exercise, 42(8), 1582-1598. doi: 10.1249/MSS.0b013e3181d2013a.

Coutts AJ, Slattery KM, Wallace LK. (2007). Practical tests for monitoring performance, fatigue and recovery in triathletes. J Sci Med Sport. 10(6):372–381. doi: 10.1016/j.jsams.2007.02.007

Enoka R. Stuart, D. (1992) Neurobiology of muscle fatigue. J Apll Physiol 72 (5): 1631- 1648. doi: 10.1152/jappl.1992.72.5.1631.

Enoka RM, Duchateau J. (2008) Muscle fatigue: what, why and how it influences muscle function. J Physiol. 586:11-23. doi: 10.1113/jphysiol.2007.139477.

Esteve-Lanao J, Rhea MR, Fleck SJ, Lucia A. Running-specific, periodized strength training attenuates loss of stride length during intense endurance running. J Strength Cond Res. 2008 Jul;22(4):1176-83. doi: 10.1519/JSC.0b013e31816a861f.

Gandevia SC, Allen GM, McKenzie DK. Central fatigue. Critical issues, quantification and practical implications. Adv Exp Med Biol. 1995;384:281-94. PMID: 8585457.

Gandevia SC. (2001). Spinal and supraspinal factors in human muscle fatigue. Physiologicals Reviews. Oct;81(4):1725-89. doi: 10.1152/physrev.2001.81.4.1725.

Gathercole R, Sporer B, Stellingwerff T, Sleivert G. (2015) Alternative counter movement jump analysis to quantify acute neuromuscular fatigue. International Journal of Sports Physiology and Performance. Jan; 10(1):84-92. doi: 10.1123/ijspp.2013-0413.

Gathercole, R. J., Stellingwerff, T., & Sporer, B. C. (2015b). Effect of acute fatigue and training adaptation on countermovement jump performance in elite snowboard cross athletes. The Journal of Strength & Conditioning Research, 29(1), 37-46. doi: 10.1519/JSC.0000000000000622.

Green, H. (1997). Mechanisms of muscle fatigue in intense exercise. Journal of Sports Sciences. 15 247-256. doi: 10.1080/026404197367254.

Gutiérrez-Dávila M, Amaro FJ, Garrido JM, Javier Rojas F. An analysis of two styles of arm action in the vertical countermovement jump. Sports Biomech. 2014 Jun;13(2):135-43. doi: 10.1080/14763141.2014.910832.

Halson SL. (2014). Monitoring training load to understand fatigue in athletes. Sports Med. 44:139—47. doi: 10.1007/s40279-014-0253-z.

Hamada, T, Sale, D.G, MacDougall, J.D. (2000). Postactivation potentiation in endurance-trained male athletes. Medicine Science Sports Exercise, 32, 403-411. doi: 10.1097/00005768-200002000-00022.

Hori N, Newton RU, Kawamori N, McGuigan MR, Kraemer WJ, Nosaka K. (2009). Reliability of performance measurements derived from ground reaction force data during countermovement jump and the influence of sampling frequency. Journal of Strength and Conditioning Research. May;23(3):874-82. doi: 10.1519/JSC.0b013e3181a00ca2.

Izquierdo, Mikel. (2008). Biomecanica y bases neuromusculares de la actividad física y el deporte. Madrid: Spain, Editorial Médica Panamericana S.A.

Kibele, A. (1998). Possibilities and limitations in the biomechanical analysis of countermovement jumps: A methodological study. Journal of Applied Biomechanics, 14, 105-117. DOI:

Laffaye G, Wagner PP, Tombleson TI. (2014). Countermovement jump height: gender and sport-specific differences in the force-time variables. Journal of Strength and Conditioning Research. Apr;28(4):1096-105. doi: 10.1519/JSC.0b013e3182a1db03.

Lindinger MI. (2006). Determinants of sarcolemmal and transverse tubular excitability in skeletal muscle: implications for high intensity exercise. Equine Comp Exerc Physiol. 2:209-217. doi: 10.1113/jphysiol.2007.132209.

Marqués-Jiménez D, Calleja-González J, Arratibel-Imaz I, Terrados N. Match Loads May Predict Neuromuscular Fatigue and Intermittent-Running Endurance Capacity Decrement after a Soccer Match. Int J Environ Res Public Health. 2022 Nov 21;19(22):15390. doi: 10.3390/ijerph192215390.

McKenna M. J., Bangsbo J., Renaud J. M. (2008). Muscle K+, Na+, and Cl disturbances and Na+-K+pump inactivation: implications for fatigue. J. Appl. Physiol. 104, 288-295. doi: 10.1152/japplphysiol.01037.2007.

McLean BD, Couuts AJ, Kelly V, McGuigan MR, Cormack SJ. (2010). Neuromuscular, endocrine, and perceptual fatigue responses during different length between-match microcycles in professional rugby league players. Int J Sports Physiol Perform. Sep; 5(3):367-83. doi: 10.1123/ijspp.5.3.367.

Mettler JA, Griffin L. (2012). Postactivation potentiation and muscular endurance training. Muscle Nerve. Mar; 45(3):416-25. doi: 10.1002/mus.22313.

Milias GA, Nomikos T, FragopoulouE, Athanasopoulos S, Antonopoulou S. (2005). Effects of eccentric exercise-induced muscle injury on blood levels of platelet activating factor (PAF)

and other inflammatory markers. EurJApplPhysiol. Dec;95(5-6):504-13. doi: 10.1007/s00421-005-0031-6.

Mougios V. Reference intervals for serum creatine kinase in athletes. Br J Sports Med. 2007 Oct;41(10):674-8. doi: 10.1136/bjsm.2006.034041.

Nuuttila OP, Nummela A, Korhonen E, Häkkinen K, Kyröläinen H. Individualized Endurance Training Based on Recovery and Training Status in Recreational Runners. Med Sci Sports Exerc. 2022 Oct 1;54(10):1690-1701. doi: 10.1249/MSS.0000000000002968

Reardon D, Hoffman JR, MAngine GT, Wells AJ, Gonzalez AM, Jitner AR, Townsend JR, McCormack WP, Stout JR, Fragala MS, Fukuda, D.H. (2014). Do Changes in Muscle Architecture Affect Post-Activation Potentiation? Journal of Sports Science and Medicine. Sept.1;13(3): 483-492. PMID: 25178394

St Clair Gibson A, Lambert ML, Noakes TD. (2001). Neural control of force output during maximal and submaximal exercise. Sports Medicine. 31(9):637-50. doi: 10.2165/00007256-200131090-00001.

Tillin, NA, David Bishop, D. (2009). Factors Modulating Post Activation Potentiation and its Effect on Performance of Subsequent Explosive Activities. Sports Med. 39 (2): 147-166. doi: 10.2165/00007256-200939020-00004.

Toumi, H., Poumarat, G., Best, T.M., Martin, A., Fairclough, J. & Benjamin, M. (2006). Fatigue and muscle tendon stiffness after stretch shortening cycle and isometric exercise. Appl Physiol Nutr Metab.; 31(5): 565-572. doi: 10.1139/h06-034.

Urhausen A, Kindermann W. (2002). Diagnosis of overtraining: what tools do we have? Sports Med. 32:95—102. doi: 10.2165/00007256-200232020-00002

Vanmeerhaeghe A, Rodriguez D. (2013). Neuromuscular risk factors of sports injury. Apunts. 'Esport Medicine. 48 (179): 109-120.

Vuorimaa, T., Virlander, R., Kurkilahti, P., Vasankari, T., & Häkkinen, K. (2006). Acute changes in muscle activation and leg extensión performance after different running exercises in elite long-distance runners. European Journal of Applied Physiology, 96, 282-291. doi: 10.1007/s00421-005-0054-z.

Warren GL, Lowe DA, Armstrong RB. (1999). Measurement tools used in the study of eccentric contraction-induced injury. Sports Med. 27:43—59. doi: 10.2165/00007256-199927010-00004.

Westerblad H, Allen DG, Bruton JD, Andrade FH, Lannergren J. (1998) Mechanisms underlying the reduction of isometric force in skeletal muscle fatigue. Acta Physiol Scand. 162:253—60. doi: 10.1046/j.1365-201X.1998.0301f.x.






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